Susan Wyllie : rechercher sur Z-Library

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1

Genetic instability occurs in the majority of young patients with colorectal cancer

Liu, Bo, Farrington, Susan M., Petersen, Gloria M., Hamilton, Stanley R., Parsons, Ramon, Papadopoulos, Nickolas, Fujiwara, Takato, Jen, Jin, Ainzler, Kenneth W., Wyllie, Andrew H.

Journal:

Nature Medicine

Année:

1995

Fichier:

PDF, 714 KB

1995

2

Clinical and veterinary trypanocidal benzoxaboroles target CPSF3

Wall, Richard J., Rico, Eva, Lukac, Iva, Zuccotto, Fabio, Elg, Sara, Gilbert, Ian H., Freund, Yvonne, Alley, M. R. K., Field, Mark C., Wyllie, Susan, Horn, David

Journal:

Proceedings of the National Academy of Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2018

3

Trypanothione biosynthesis in Leishmania major

Sandra L. Oza, Matthew P. Shaw, Susan Wyllie, Alan H. Fairlamb

Journal:

Molecular and Biochemical Parasitology

Année:

2005

Langue:

english

Fichier:

PDF, 418 KB

english, 2005

4

Refinement of techniques for the propagation of Leishmania donovani in hamsters

Susan Wyllie, Alan H. Fairlamb

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 154 KB

english, 2006

5

Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis

Wyllie, Susan, Thomas, Michael, Patterson, Stephen, Crouch, Sabrinia, De Rycker, Manu, Lowe, Rhiannon, Gresham, Stephanie, Urbaniak, Michael D., Otto, Thomas D., Stojanovski, Laste, Simeons, Frederick

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 2.76 MB

english, 2018

6

APC EXPRESSION IN NORMAL HUMAN TISSUES

MIDGLEY, CAROL A., WHITE, SUSAN, HOWITT, RACHEL, SAVE, VICKI, DUNLOP, MALCOLM G., HALL, PETER A., LANE, DAVID P., WYLLIE, ANDREW H., BUBB, VIVIEN J.

Journal:

The Journal of Pathology

Année:

1997

Langue:

english

Fichier:

PDF, 3.80 MB

english, 1997

7

Germline APC mutation (Gln1317) in a cancer-prone family that does not result in familial adenomatous polyposis

Susan White, Vivien J. Bubb, Andrew H. Wyllie

Journal:

Genes, Chromosomes and Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 658 KB

english, 1996

8

Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer

Lucy J. Curtis, Izabela B. Georgiades, Susan White, Colin C. Bird, David J. Harrison, Andrew H. Wyllie

Journal:

The Journal of Pathology

Année:

2000

Langue:

english

Fichier:

PDF, 124 KB

english, 2000

9

Evidence for an age-related influence of microsatellite instability on colorectal cancer survival

Susan M. Farrington, Aileen J. McKinley, Andrew D. Carothers, Christopher Cunningham, Vivien J. Bubb, Linda Sharp, Andrew H. Wyllie, Malcolm G. Dunlop

Journal:

International Journal of Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 123 KB

english, 2002

10

Identifying regulators of transcription in an obligate intracellular pathogen: a metal-dependent repressor in Chlamydia trachomatis

Susan Wyllie, Jane E. Raulston

Journal:

Molecular Microbiology

Année:

2001

Langue:

english

Fichier:

PDF, 135 KB

english, 2001

11

Chemical and genetic validation of dihydrofolate reductase–thymidylate synthase as a drug target in African trypanosomes

Natasha Sienkiewicz, Szymon Jarosławski, Susan Wyllie, Alan H. Fairlamb

Journal:

Molecular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 665 KB

english, 2008

12

Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods

Susan Wyllie, Sandra L. Oza, Stephen Patterson, Daniel Spinks, Stephen Thompson, Alan H. Fairlamb

Journal:

Molecular Microbiology

Année:

2009

Langue:

english

Fichier:

PDF, 287 KB

english, 2009

13

ATP-dependent ligases in trypanothione biosynthesis – kinetics of catalysis and inhibition by phosphinic acid pseudopeptides

Sandra L. Oza, Shoujun Chen, Susan Wyllie, James K. Coward, Alan H. Fairlamb

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 743 KB

english, 2008

14

A comparative study of methylglyoxal metabolism in trypanosomatids

Neil Greig, Susan Wyllie, Stephen Patterson, Alan H. Fairlamb

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 349 KB

english, 2009

15

Early-onset colorectal cancer with stable microsatellite DNA and near-diploid chromosomes

Dunlop, Malcolm G, Wyllie, Andrew H, Chan, Tsun Leung, Curtis, Lucy C, Leung, Suet Yi, Farrington, Susan M, Ho, Judy WC, Chan, Annie SY, Lam, Polly WY, Tse, Chun Wah

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 372 KB

english, 2001

16

On the nature of the receptor mediating the action of 5-hydroxytryptamine in potentiating responses of the mouse urinary bladder strip to electrical stimulation

Susan E. Holt, Marie Cooper, J. H. Wyllie

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

1986

Langue:

english

Fichier:

PDF, 789 KB

english, 1986

17

Differential toxicity of antimonial compounds and their effects on glutathione homeostasis in a human leukaemia monocyte cell line

Susan Wyllie, Alan H. Fairlamb

Journal:

Biochemical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 574 KB

english, 2006

18

Quinol derivatives as potential trypanocidal agents

Amy Capes, Stephen Patterson, Susan Wyllie, Irene Hallyburton, Iain T. Collie, Andrew J. McCarroll, Malcolm F.G. Stevens, Julie A. Frearson, Paul G. Wyatt, Alan H. Fairlamb, Ian H. Gilbert

Journal:

Bioorganic & Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 482 KB

english, 2012

19

Comparative proteomics profiling of a gentamicin-attenuated Leishmania infantum cell line identifies key changes in parasite thiol-redox metabolism

Hamid Daneshvar, Susan Wyllie, Stephen Phillips, Paul Hagan, Richard Burchmore

Journal:

Journal of Proteomics

Année:

2012

Langue:

english

Fichier:

PDF, 669 KB

english, 2012

20

Mapping the functional synthetase domain of trypanothione synthetase from Leishmania major

Sandra L. Oza, Susan Wyllie, Alan H. Fairlamb

Journal:

Molecular and Biochemical Parasitology

Année:

2006

Langue:

english

Fichier:

PDF, 269 KB

english, 2006

21

Elevated levels of tryparedoxin peroxidase in antimony unresponsive Leishmania donovani field isolates

Susan Wyllie, Goutam Mandal, Neeloo Singh, Shyam Sundar, Alan H. Fairlamb, Mitali Chatterjee

Journal:

Molecular and Biochemical Parasitology

Année:

2010

Langue:

english

Fichier:

PDF, 144 KB

english, 2010

22

Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome

Deuan C. Jones, Magnus S. Alphey, Susan Wyllie, Alan H. Fairlamb

Journal:

Molecular Microbiology

Année:

2012

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2012

23

Evidence for purinergic transmission in mouse bladder and for modulation of responses to electrical stimulation by 5-hydroxytryptamine

Susan E. Holt, Marie Cooper, John H. Wyllie

Journal:

European Journal of Pharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 469 KB

english, 1985

24

Methylglyoxal metabolism in trypanosomes and leishmania

Susan Wyllie, Alan H. Fairlamb

Journal:

Seminars in Cell & Developmental Biology

Année:

2011

Langue:

english

Fichier:

PDF, 380 KB

english, 2011

25

The role of resuscitation drugs and placental transfusion in the delivery room management of newborn infants

Jonathan Wyllie, Susan Niermeyer

Journal:

Seminars in Fetal and Neonatal Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 171 KB

english, 2008

26

Norspermidine Is Not a Self-Produced Trigger for Biofilm Disassembly

Hobley, Laura, Kim, Sok Ho, Maezato, Yukari, Wyllie, Susan, Fairlamb, Alan H., Stanley-Wall, Nicola R., Michael, Anthony J.

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2014

27

Nitro drugs for the treatment of trypanosomatid diseases: past, present, and future prospects

Patterson, Stephen, Wyllie, Susan

Journal:

Trends in Parasitology

Année:

2014

Langue:

english

Fichier:

PDF, 529 KB

english, 2014

28

Absence of abnormalities of the c-erbB-1 and c-erbB-2 proto-oncogenes in human thyroid neoplasia

Lemoine, Nick R., Wyllie, Fiona S., Lillehaug, Johan R., Staddon, Susan L., Hughes, Christine M., Aasland, Rein, Shaw, Jonathan, Varhaug, Jan E., Brown, Christopher L., Gullick, William J.

Journal:

European Journal of Cancer and Clinical Oncology

Année:

1990

Langue:

english

Fichier:

PDF, 366 KB

english, 1990

29

APC Mutations in Colorectal Tumors with Mismatch Repair Deficiency

Jian Huang, Nickolas Papadopoulos, Aileen J. McKinley, Susan M. Farrington, Lucy J. Curtis, Andrew H. Wyllie, Shu Zheng, James K. V. Willson, Sanford D. Markowitz, Pat Morin, Kenneth W. Kinzler, Bert

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1996

30

Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy

Ong, Han B., Sienkiewicz, Natasha, Wyllie, Susan, Patterson, Stephen, Fairlamb, Alan H.

Journal:

Molecular Microbiology

Année:

2013

Langue:

english

Fichier:

PDF, 399 KB

english, 2013

31

Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei

Ong, Han B., Lee, Wai S., Patterson, Stephen, Wyllie, Susan, Fairlamb, Alan H.

Journal:

Molecular Microbiology

Année:

2015

Langue:

english

Fichier:

PDF, 3.94 MB

english, 2015

32

LEVELS OF SIGNIFICANCE FOR FUZZY IMPLICATION

BANDLER, WYLLIS, HRUSKA, SUSAN I.

Journal:

International Journal of Uncertainty Fuzziness and Knowledge-Based Systems

Année:

1994

Langue:

english

Fichier:

PDF, 380 KB

english, 1994

33

Arsenic, antimony, and Leishmania: has arsenic contamination of drinking water in India led to treatment- resistant kala-azar?

Perry, Meghan, Wyllie, Susan, Prajapati, Vijay, Menten, Joris, Raab, Andrea, Feldmann, Joerg, Chakraborti, Dipankar, Sundar, Shyam, Boelaert, Marleen, Picado, Albert, Fairlamb, Alan

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 64 KB

english, 2015

34

Visceral Leishmaniasis and Arsenic: An Ancient Poison Contributing to Antimonial Treatment Failure in the Indian Subcontinent?

Perry, Meghan R., Wyllie, Susan, Prajapati, Vijay Kumar, Feldmann, Joerg, Sundar, Shyam, Boelaert, Marleen, Fairlamb, Alan H., Büscher, Philippe

Journal:

PLoS Neglected Tropical Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 463 KB

english, 2011

35

Biochemical and genetic characterization of Trypanosoma cruzi N -myristoyltransferase

Roberts, Adam J., Torrie, Leah S., Wyllie, Susan, Fairlamb, Alan H.

Journal:

Biochemical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 786 KB

english, 2014

36

Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes

Bruhn, David F., Wyllie, Susan, Rodríguez-Cortés, Adaris, Carrillo, Angela K., Rakesh,, Guy, Kiplin, Fairlam, Alan H., Lee, Richard E.

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2015

Langue:

english

Fichier:

PDF, 464 KB

english, 2015

37

Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei

Wyllie, Susan, Foth, Bernardo J., Kelner, Anna, Sokolova, Antoaneta Y., Berriman, Matthew, Fairlamb, Alan H.

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 633 KB

english, 2016

38

Growth Abnormalities Persist in Newly Diagnosed Children With Crohn Disease Despite Current Treatment Paradigms

Pfefferkorn, Marian, Burke, Georgine, Griffiths, Anne, Markowitz, James, Rosh, Joel, Mack, David, Otley, Anthony, Kugathasan, Subra, Evans, Jonathan, Bousvaros, Athos, Moyer, M Susan, Wyllie, Robert,

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Année:

2009

Langue:

english

Fichier:

PDF, 373 KB

english, 2009

39

Trypanothione-dependent glyoxalase I in Trypanosoma cruzi

Greig, Neil, Wyllie, Susan, Vickers, Tim J., Fairlamb, Alan H.

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 308 KB

english, 2006

40

Snapshot Profiling of the Antileishmanial Potency of Lead Compounds and Drug Candidates against Intracellular Leishmania donovani Amastigotes, with a Focus on Human-Derived Host Cells

Koniordou, Markela, Patterson, Stephen, Wyllie, Susan, Seifert, Karin

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 491 KB

english, 2017

41

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Field, Mark C., Horn, David, Fairlamb, Alan H., Ferguson, Michael A. J., Gray, David W., Read, Kevin D., De Rycker, Manu, Torrie, Leah S., Wyatt, Paul G., Wyllie, Susan, Gilbert, Ian H.

Journal:

Nature Reviews Microbiology

Année:

2017

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2017

42

Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Field, Mark C., Horn, David, Fairlamb, Alan H., Ferguson, Michael A. J., Gray, David W., Read, Kevin D., De Rycker, Manu, Torrie, Leah S., Wyatt, Paul G., Wyllie, Susan, Gilbert, Ian H.

Journal:

Nature Reviews Microbiology

Année:

2017

Fichier:

PDF, 51 KB

2017

43

Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani

Torrie, Leah S., Brand, Stephen, Robinson, David A., Ko, Eun Jung, Stojanovski, Laste, Simeons, Frederick R. C., Wyllie, Susan, Thomas, John, Ellis, Lucy, Osuna-Cabello, Maria, Epemolu, Ola, Nühs, And

Journal:

ACS Infectious Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 4.53 MB

english, 2017

44

Anti-trypanosomal 8-hydroxyl naphthyridines are chelators of divalent transition metals

Wall, Richard J., Moniz, Sonia, Thomas, Michael G., Norval, Suzanne, Ko, Eun-Jung, Marco, Maria, Miles, Timothy J., Gilbert, Ian H., Horn, David, Fairlamb, Alan H., Wyllie, Susan

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2018

45

Author Correction: Anti-trypanosomatid drug discovery: an ongoing challenge and a continuing need

Field, Mark C., Horn, David, Fairlamb, Alan H., Ferguson, Michael A. J., Gray, David W., Read, Kevin D., De Rycker, Manu, Torrie, Leah S., Wyatt, Paul G., Wyllie, Susan, Gilbert, Ian H.

Journal:

Nature Reviews Microbiology

Année:

2018

Fichier:

PDF, 140 KB

2018

46

Development of Chemical Proteomics for the Folateome and Analysis of the Kinetoplastid Folateome

Webster, Lauren A., Thomas, Michael, Urbaniak, Michael, Wyllie, Susan, Ong, Han, Tinti, Michele, Fairlamb, Alan H., Boesche, Markus, Ghidelli-Disse, Sonja, Drewes, Gerard, Gilbert, Ian H.

Journal:

ACS Infectious Diseases

Année:

2018

Langue:

english

Fichier:

PDF, 3.99 MB

english, 2018